Glycosyltransferase-Like Protein LARGE1 (LARGE1) Antibody (PE)
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Description
LARGE1 Antibody is a Mouse Monoclonal against LARGE1.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Target: Glycosyltransferase-Like Protein LARGE1 (LARGE1) Immunogen: Recombinant fragment of Human LARGE1 (amino acids 35-142). |
| Host | Mouse |
| Reactivity | Human |
| Detection Method | Laser Line: 550 Excitation/Emission: 565/575 |
| Assay Type | Concentration: 0.1 mg/ml |
| Recommended Dilution | FCM: 1-5 μg/ml. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Monoclonal |
| Conjugation | PE |
| Isotype | IgG2b |
| Clone ID | X419 |
| Size 1 | 0.1 mg |
| Tested Applications | FCM |
| Buffer | Stabilizing PBS solution containing 15 mM sodium azide. |
| Availability | Shipped within 5-12 working days. |
| Storage | Store in the dark at 2-8°C. Avoid exposure to light. Do not freeze. |
| Dry Ice | No |
| UniProt ID | O95461 |
| Gene ID | 9215 |
| Background | Antibody anti-LARGE1 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Descripción
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LARGE1 antibody
Bifunctional glycosyltransferase with both xylosyltransferase and beta-1,3-glucuronyltransferase activities involved in the biosynthesis of the phosphorylated O-mannosyl trisaccharide(N-acetylgalactosamine-beta-3-N-acetylglucosamine-beta-4-(phosphate-6-)mannose), a carbohydrate structure present in alpha-dystroglycan(DAG1)(PubMed:22223806). Phosphorylated O-mannosyl trisaccharid is required for binding laminin G-like domain-containing extracellular proteins with high affinity and plays a key role in skeletal muscle function and regeneration. LARGE elongates the glucuronyl-beta-1,4-xylose-beta disaccharide primer structure initiated by B3GNT1/B4GAT1 by adding repeating units [-3-Xylose-alpha-1,3-GlcA-beta-1-] to produce a heteropolysaccharide(PubMed:25279699).
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Glycosyltransferase-Like Protein LARGE1 (LARGE1) Antibody
LARGE1 Antibody is a Mouse Monoclonal against LARGE1.
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