Hemoglobin subunit alpha 2 Antibody

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Description
HBA2 located on chromosome 16 spans about 30 kb and includes seven loci: 5' zeta pseudozeta mu pseudoalpha-1 alpha-2 alpha-1 theta 3'. The alpha-2 (HBA2) and alpha-1 (HBA1) coding sequences are identical. These genes differ slightly over the 5' untranslated regions and the introns, but they differ significantly over the 3' untranslated regions. Two alpha chains plus two beta chains constitute HbA, which in normal adult life comprises about 97% of the total hemoglobin; alpha chains combine with delta chains to constitute HbA-2, which with HbF (fetal hemoglobin) makes up the remaining 3% of adult hemoglobin. Alpha thalassemias result from deletions of each of the alpha genes as well as deletions of both HBA2 and HBA1; some nondeletion alpha thalassemias have also been reported.
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Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Hemoglobin subunit alpha 2 |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Recommended Dilution | WB: 1/1000, FCM: 1/25. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Size 1 | 50 µl |
| Size 2 | 200 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB, FCM |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P69905 |
| NCBI Accession | NP_000508.1, NP_000549.1 |
| Background | Antibody anti-HBA |
| Status | RUO |
Descripción
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Hemoglobin subunit alpha 2 Antibody
HBA2 Antibody is a Rabbit Polyclonal Antibody against HBA2.
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Hemoglobin subunit alpha 2 Antibody
HBA2 located on chromosome 16 spans about 30 kb and includes seven loci: 5' zeta pseudozeta mu pseudoalpha-1 alpha-2 alpha-1 theta 3'. The alpha-2 (HBA2) and alpha-1 (HBA1) coding sequences are identical. These genes differ slightly over the 5' untranslated regions and the introns, but they differ significantly over the 3' untranslated regions. Two alpha chains plus two beta chains constitute HbA, which in normal adult life comprises about 97% of the total hemoglobin; alpha chains combine with delta chains to constitute HbA-2, which with HbF (fetal hemoglobin) makes up the remaining 3% of adult hemoglobin. Alpha thalassemias result from deletions of each of the alpha genes as well as deletions of both HBA2 and HBA1; some nondeletion alpha thalassemias have also been reported.
Ver Producto