Hereditary Hemochromatosis Protein (HFE) Antibody
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
Description
The protein encoded by this gene is a membrane protein that is similar to MHC class I-type proteins and associates with beta2-microglobulin (beta2M).It is thought that this protein functions to regulate iron absorption by regulating the interaction of the transferrin receptor with transferrin.The iron storage disorder, hereditary haemochromatosis, is a recessive genetic disorder that results from defects in this gene.At least nine alternatively spliced variants have been described for this gene.Additional variants have been found but their full-length nature has not been determined.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Hereditary Hemochromatosis Protein (HFE) |
| Host | Mouse |
| Reactivity | Human |
| Recommended Dilution | ELISA: 1/10000, IF/ICC: 1/200 - 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Monoclonal |
| Conjugation | Unconjugated |
| Isotype | IgG1 |
| Purification | Unpurified ascites. |
| Size 1 | 100 µl |
| Form | Liquid |
| Tested Applications | ELISA, IF/ICC |
| Buffer | Ascitic fluid containing 0.03% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q30201 |
| Gene ID | 3077 |
| OMIM | 176200 |
| Background | Antibody anti-HFE |
| Status | RUO |
| Note | Concentration: Not determined. - |
Descripción
Related Products
HFE antibody
Binds to transferrin receptor(TFR) and reduces its affinity for iron-loaded transferrin.
Ver Producto
Hereditary Hemochromatosis Protein (HFE) Antibody
HFE Antibody is a Rabbit Polyclonal antibody against HFE. The protein encoded by this gene is a membrane protein that is similar to MHC class I-type proteins and associates with beta2-microglobulin (beta2M). It is thought that this protein functions to regulate iron absorption by regulating the interaction of the transferrin receptor with transferrin. The iron storage disorder, hereditary haemochromatosis, is a recessive genetic disorder that results from defects in this gene. At least nine alternatively spliced variants have been described for this gene. Additional variants have been found but their full-length nature has not been determined. [provided by RefSeq, Jul 2008].
Ver Producto
Hereditary Hemochromatosis Protein (HFE) Antibody
The protein encoded by this gene is a membrane protein that is similar to MHC class I-type proteins and associates with beta2-microglobulin (beta2M).It is thought that this protein functions to regulate iron absorption by regulating the interaction of the transferrin receptor with transferrin.The iron storage disorder, hereditary haemochromatosis, is a recessive genetic disorder that results from defects in this gene.At least nine alternatively spliced variants have been described for this gene.Additional variants have been found but their full-length nature has not been determined.
Ver Producto