Human A Disintegrin And Metalloprotease 20 (ADAM20) Protein

234€ (10 µg)
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name
Human A Disintegrin And Metalloprotease 20 (ADAM20) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx065060
tested applications
WB, SDS-PAGE
Description
Human ADAM20 is a recombinant Human protein expressed in E. coli.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | A Disintegrin And Metalloprotease 20 (ADAM20) |
| Host | E. coli |
| Assay Type | Activity: Not tested Sequence Fragment: His367-Gly615 Tag: N-terminal His tag |
| Origin | Human |
| Conjugation | Unconjugated |
| Observed MW | Calculated MW: 29.0 kDa |
| Expression | Recombinant |
| Purity | > 95% |
| Size 1 | 10 µg |
| Size 2 | 50 µg |
| Size 3 | 100 µg |
| Size 4 | 200 µg |
| Size 5 | 500 µg |
| Form | Lyophilized |
| Tested Applications | WB, SDS-PAGE |
| Buffer | Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300. |
| Availability | Shipped within 5-7 working days. |
| Storage | Store lyophilized form at 2-8°C for up to 1 month. For longer periods, store lyophilized or liquid at -80°C. Avoid repeated freeze–thaw cycles. |
| Dry Ice | No |
| UniProt ID | O43506 |
| Alias | EC 3.4.24.58, EC 3.4.24,A Disintegrin And Metalloproteinase Domain 20,adam-20 |
| Background | Protein ADAM20 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex. Concentration: Prior to lyophilization: 200 µg/ml |
Descripción
ADAM20 (A Disintegrin And Metalloproteinase 20) is a member of the ADAM family. These proteins are primarily involved in various biological processes, including cell adhesion, migration, proteolysis, and signaling. ADAM20 is a type I transmembrane glycoprotein with a complex structure consisting of several distinct domains, including a metalloproteinase domain, disintegrin domain, cysteine-rich domain, epidermal growth factor-like domain, transmembrane domain, and cytoplasmic tail. The metalloproteinase domain of ADAM20 suggests its potential involvement in proteolytic processing of proteins within the extracellular matrix or on the cell surface. However, the specific functions and substrates of ADAM20 are not as well characterized compared to some other members of the ADAM family. ADAM20 is specifically implicated in reproductive biology, particularly in sperm development and function. It is one of the several ADAM proteins that play critical roles in fertilization.
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