Human ADAMTS-like protein 5 (ADAMTSL5) ELISA Kit

Este producto es parte de ADAMTSL - ADAMTS-like protein
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715€ (96 tests)

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935106861
info@markelab.com
name
Human ADAMTS-like protein 5 (ADAMTSL5) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx503077
tested applications
ELISA

Description

Human ADAMTS-like protein 5 (ADAMTSL5) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human ADAMTS-like protein 5 (ADAMTSL5) concentrations in serum, plasma and other biological fluids.

Documents del producto

Instrucciones
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Data sheet
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Product specifications

Category
ELISA Kits
Immunogen Target
ADAMTS-like protein 5 (ADAMTSL5)
Reactivity
Human
Detection Method
Colorimetric
Assay Data
Quantitative
Assay Type
Sandwich
Test Range
0.312 ng/ml - 20 ng/ml
Sensitivity
< 0.15 ng/ml
Recommended Dilution
Optimal dilutions/concentrations should be determined by the end user.
Size 1
96 tests
Form
Standard Form: Lyophilized
Tested Applications
ELISA
Sample Type
Serum, plasma and other biological fluids.
Availability
Shipped within 5-15 working days.
Storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
Dry Ice
No
UniProt ID
Q6ZMM2
Alias
Thrombospondin type-1 domain-containing protein 6,ADAMTSL-5
Background
Elisa Kits for: ADAMTSL5
Status
RUO
Note
THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
The stability of the kit is determined by the rate of activity loss. The loss rate is less than 5% within the expiration date under appropriate storage conditions. To minimize performance fluctuations, operation procedures and lab conditions should be strictly controlled. It is also strongly suggested that the whole assay is performed by the same user throughout.

Descripción

ADAMTSL5 is an extracellular protein that regulates ECM structure and fibrillin microfibril assembly. It is particularly notable for its involvement in cartilage biology and has been identified as a key factor in the pathogenesis of osteoarthritis. ADAMTSL5 interacts with cartilage ECM components such as aggrecan and modulates TGF-β signaling pathways, which influence cartilage homeostasis. Studies have shown that ADAMTSL5 expression increases in osteoarthritic cartilage, suggesting its role in disease progression. Its regulatory function in ECM integrity highlights its importance in skeletal and joint health, making it a potential biomarker and therapeutic target in degenerative joint diseases.

Related Products

abx503077

Human ADAMTS-like protein 5 (ADAMTSL5) ELISA Kit

Human ADAMTS-like protein 5 (ADAMTSL5) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human ADAMTS-like protein 5 (ADAMTSL5) concentrations in serum, plasma and other biological fluids.

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