Human Anaphase-promoting complex subunit 7 (ANAPC7) ELISA Kit

Este producto es parte de ANAPC - Anaphase-promoting complex subunit
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715€ (96 tests)

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935106861
info@markelab.com
name
Human Anaphase-promoting complex subunit 7 (ANAPC7) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx502126
tested applications
ELISA

Description

Human Anaphase-promoting complex subunit 7 (ANAPC7) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Anaphase-promoting complex subunit 7 (ANAPC7) concentrations in serum, plasma, tissue homogenates, cell culture supernatants and other biological fluids.

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
ELISA Kits
Immunogen Target
Anaphase-promoting complex subunit 7 (ANAPC7)
Reactivity
Human
Detection Method
Colorimetric
Assay Data
Quantitative
Test Range
0.156 ng/ml - 10 ng/ml
Recommended Dilution
Optimal dilutions/concentrations should be determined by the end user.
Size 1
96 tests
Form
Standard Form: Lyophilized
Tested Applications
ELISA
Sample Type
Serum, plasma, tissue homogenates, cell culture supernatants and other biological fluids.
Availability
Shipped within 5-15 working days.
Storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
Dry Ice
No
UniProt ID
Q9UJX3
Alias
ANAPC7,APC7,Cyclosome subunit 7
Background
Elisa Kits for: ANAPC7
Status
RUO
Note
THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
The stability of the kit is determined by the rate of activity loss. The loss rate is less than 5% within the expiration date under appropriate storage conditions. To minimize performance fluctuations, operation procedures and lab conditions should be strictly controlled. It is also strongly suggested that the whole assay is performed by the same user throughout.

Descripción

ANAPC7 is a structural and functional subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C), where it supports the overall assembly and function of the complex. ANAPC7 acts as a scaffold protein, interacting with other subunits to stabilize the architecture of APC/C and ensure efficient ubiquitin transfer to its substrates. It contributes to the recognition and ubiquitination of key cell cycle regulators, including cyclin B and securin, promoting their degradation to trigger the metaphase-to-anaphase transition and mitotic exit. ANAPC7 is essential for maintaining cell cycle fidelity and genomic stability. Dysregulation of ANAPC7 impairs APC/C function, leading to defective chromosome segregation, aneuploidy, and increased susceptibility to cancer. Emerging evidence suggests that ANAPC7 may also play a role in stress responses and DNA damage repair, linking it to broader cellular regulatory networks. Its critical role in APC/C function highlights its significance in both normal cell division and tumor suppression.

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