Human APPL2 (DCC-Interacting Protein 13-Beta) ELISA Kit
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Name
Human APPL2 (DCC-Interacting Protein 13-Beta) ELISA Kit
Category
ELISA Kits
Provider
FineTest
Reference
EH6387
Tested Applications
ELISA
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | ELISA Kits |
| Reactivity | Human |
| Detection Method | Colorimetric |
| Assay Data | 4 hours |
| Assay Type | Sandwich ELISA, Double Antibody |
| Test Range | 0.156-10ng/ml |
| Sensitivity | 0.094ng/ml |
| Size 1 | 96T |
| Tested Applications | ELISA |
| Sample Type | Serum, Plasma, Cell Culture Supernatant, cell or tissue lysate, Other liquid samples |
| Availability | Shipped within 10-14 working days. |
| Storage | 2-8 °C for 12 months |
| UniProt ID | Q8NEU8 |
| Alias | DIP13B,Dip13-beta,Adapter protein containing PH domain, PTB domain and leucine zipper motif 2 |
| Background | Elisa kits for APPL2 |
| Status | RUO |
Background
APPL2 (Phosphotyrosine Interacting with PH Domain and Leucine Zipper 2) is another member of the APPL protein family, similar to APPL1. Like APPL1, APPL2 also contains a pleckstrin homology (PH) domain and a leucine zipper, enabling it to interact with phosphotyrosine-containing proteins. APPL2 is involved in a wide range of cellular processes including endocytosis, signal transduction, and the regulation of vesicular trafficking. It is particularly important in regulating the function of the insulin receptor and in modulating signaling pathways that control cell growth, survival, and metabolism. APPL2 is known to affect cellular responses to growth factors and contributes to the regulation of neuronal function and plasticity. Its role in intracellular signaling makes it a relevant protein in understanding diseases like diabetes and neurodegenerative conditions.
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