Human ATP Binding Cassette Transporter A3 (ABCA3) ELISA Kit

Este producto es parte de ABCA3 - ATP Binding Cassette Transporter A3
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715€ (96 tests)

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935106861
info@markelab.com
name
Human ATP Binding Cassette Transporter A3 (ABCA3) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx150499
tested applications
ELISA

Description

Human ATP Binding Cassette Transporter A3 (ABCA3) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human ATP Binding Cassette Transporter A3 (ABCA3) concentrations in tissue homogenates, cell lysates and other biological fluids. This assay has high sensitivity and excellent specificity for detection of ATP Binding Cassette Transporter A3 (ABCA3)

Documents del producto

Instrucciones
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Data sheet
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Product specifications

Category
ELISA Kits
Immunogen Target
ATP Binding Cassette Transporter A3 (ABCA3)
Reactivity
Human
Detection Method
Colorimetric
Assay Data
Quantitative
Assay Type
Sandwich
Test Range
0.156 ng/ml - 10 ng/ml
Sensitivity
< 0.07 ng/ml
Recommended Dilution
Optimal dilutions/concentrations should be determined by the end user.
Size 1
96 tests
Size 2
5 × 96 tests
Size 3
10 × 96 tests
Form
Standard Form: Lyophilized
Tested Applications
ELISA
Sample Type
Tissue homogenates, cell lysates and other biological fluids.
Availability
Shipped within 5-7 working days.
Storage
Shipped at 4°C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
Dry Ice
No
UniProt ID
Q99758
Gene ID
21
OMIM
601615
Alias
ABC-C,ABC3,LBM180,SMDP3
Background
Elisa Kits for: ABCA3
Status
RUO
Note
THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
The stability of the kit is determined by the rate of activity loss. The loss rate is less than 5% within the expiration date under appropriate storage conditions. To minimize performance fluctuations, operation procedures and lab conditions should be strictly controlled. It is also strongly suggested that the whole assay is performed by the same user throughout.

Descripción

ABCA3 is a critical protein in pulmonary surfactant production, predominantly expressed in alveolar type II epithelial cells in the lungs. It plays an essential role in transporting phospholipids and cholesterol into lamellar bodies, which are specialized organelles where surfactant is stored before secretion. ABCA3 utilizes ATP hydrolysis to facilitate lipid transport, ensuring the proper composition and function of surfactant, which reduces surface tension in the alveoli and prevents lung collapse. Mutations in the ABCA3 gene are associated with surfactant metabolism disorders, including neonatal respiratory distress syndrome and interstitial lung disease. These conditions are characterized by impaired surfactant production, leading to respiratory failure. ABCA3’s function in lipid transport and its critical role in pulmonary physiology underscore its importance in respiratory health.

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