Human Neurobeachin (NBEA) ELISA Kit

715€ (96 tests)
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935106861
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name
Human Neurobeachin (NBEA) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx385207
tested applications
ELISA
Description
Human Neurobeachin (NBEA) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human NBEA concentrations in tissue homogenates, cell lysates and other biological fluids.
Documents del producto
Product specifications
| Category | ELISA Kits |
| Immunogen Target | Neurobeachin (NBEA) |
| Reactivity | Human |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Assay Type | Sandwich |
| Test Range | 0.156 ng/ml - 10 ng/ml |
| Sensitivity | < 0.04 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Form | Standard Form: Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
| Availability | Shipped within 5-15 working days. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | Q8NFP9 |
| Gene ID | 26960 |
| OMIM | 604889 |
| Alias | BCL8B,LYST2,NEDEGE,Protein BCL8B,Lysosomal-trafficking regulator 2 |
| Background | Elisa Kits for: NBEA |
| Status | RUO |
| Note | This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. The stability of the kit is determined by the rate of activity loss. The loss rate is less than 5% within the expiration date under appropriate storage conditions. To minimize performance fluctuations, operation procedures and lab conditions should be strictly controlled. It is also strongly suggested that the whole assay is performed by the same user throughout. |
Descripción
Neurobeachin (NBEA) is a multi-domain protein involved in the regulation of synaptic function, neuronal signaling, and cell adhesion NBEA is particularly abundant in the brain, where it plays a role in neuronal growth, synaptic plasticity, and the maintenance of neuronal structure It interacts with a variety of proteins involved in synaptic signaling and vesicle trafficking, contributing to the organization of the postsynaptic density and the regulation of neurotransmitter receptor trafficking NBEA is essential for the proper function of neurons, particularly in areas involved in learning and memory, and its dysfunction is linked to neurological disorders such as neurodevelopmental disorders and intellectual disability Mutations in NBEA disrupt neuronal connectivity and signaling, leading to impaired cognitive function Understanding NBEA’s role in neuronal health could provide insights into therapies for treating neurodevelopmental and neurodegenerative diseases
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