Human Nucleoporin 205 kDa (NUP205) Protein
234€ (10 µg)
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name
Human Nucleoporin 205 kDa (NUP205) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx068360
tested applications
WB, SDS-PAGE
Description
Human Nucleoporin 205 kDa (NUP205) is a recombinant Human protein expressed in E. coli.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | Nucleoporin 205kDa (NUP205) |
| Host | E. coli |
| Assay Type | Activity: Not tested Sequence Fragment: Asp1735-Val2000 Tag: N-terminal His tag |
| Origin | Human |
| Conjugation | Unconjugated |
| Observed MW | Calculated MW: 34.2 kDa |
| Expression | Recombinant |
| Purity | > 95% |
| Size 1 | 10 µg |
| Size 2 | 50 µg |
| Size 3 | 100 µg |
| Size 4 | 200 µg |
| Size 5 | 500 µg |
| Form | Lyophilized |
| Tested Applications | WB, SDS-PAGE |
| Buffer | Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300. |
| Availability | Shipped within 5-7 working days. |
| Storage | Store lyophilized form at 2-8°C for up to 1 month. For longer periods, store lyophilized or liquid at -80°C. Avoid repeated freeze–thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q92621 |
| Alias | NPHS13,C7orf14, Nuclear pore complex protein Nup205,205 kDa nucleoporin,chromosome 7 open reading frame 14 |
| Background | Protein NUP205 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex. Concentration: Prior to lyophilization: 200 µg/ml |
Descripción
Nucleoporin 205 (NUP205) is a key structural component of the nuclear pore complex, contributing to the formation of the nuclear pore's central channel NUP205 works with other nucleoporins to regulate the transport of large macromolecules, such as RNA and proteins, between the nucleus and the cytoplasm It plays an important role in maintaining the selectivity and efficiency of molecular exchange, essential for processes like gene expression, cell signaling, and cellular stress responses NUP205 is involved in regulating the movement of critical proteins, such as transcription factors and cell cycle regulators, that are essential for maintaining normal cellular function Dysregulation of NUP205 is linked to several diseases, including cancers, where impaired nucleocytoplasmic transport contributes to abnormal gene expression and tumor progression Additionally, NUP205’s function in maintaining the stability and structure of the nuclear pore is critical for nuclear envelope integrity during cell division
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