Killer Cell Immunoglobulin Like Receptor 2DS4 (KIR2DS4) Antibody (APC)
689€ (100 tests)
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
935106861
info@markelab.com
name
Killer Cell Immunoglobulin Like Receptor 2DS4 (KIR2DS4) Antibody (APC)
category
Primary Antibodies
provider
Abbexa
reference
abx270625
tested applications
FCM
Description
Killer Cell Immunoglobulin Like Receptor 2DS4 (KIR2DS4) Antibody (APC) is a Rabbit Polyclonal Antibody conjugated to APC against Killer Cell Immunoglobulin Like Receptor 2DS4 (KIR2DS4) for use in flow cytometry.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Target: Killer Cell Immunoglobulin Like Receptor 2DS4 (KIR2DS4) |
| Host | Rabbit |
| Reactivity | Human |
| Detection Method | Laser Line: 647 Excitation/Emission: 651/660 |
| Recommended Dilution | FCM: 1-5 µl/106 cells. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | APC |
| Isotype | IgG |
| Purification | Purified by antigen-specific affinity chromatography. |
| Size 1 | 100 tests |
| Size 2 | 200 tests |
| Size 3 | 500 tests |
| Form | Liquid |
| Tested Applications | FCM |
| Buffer | 0.01 M PBS, pH 7.4, containing 0.05% Proclin-300, 50% glycerol. |
| Availability | Please enquire. |
| Storage | Aliquot and store at 2°C to 8°C upon receipt. Avoid exposure to light. |
| Dry Ice | No |
| Alias | CD158 antigen-like family member I,KKA3,KIR1D,Natural killer-associated transcript 8,NKAT8,CD158I,KIR412,NKAT-8,KIR-2DS4,P58 natural killer cell receptor clones CL-39/CL-17 |
| Background | Antibody anti-KIR2DS4 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Descripción
Killer cell immunoglobulin-like receptor 2DS4 (KIR2DS4) is part of the Killer-cell Immunoglobulin-like Receptor (KIR) family, which plays a central role in the immune system, specifically in regulating natural killer (NK) cells and certain T-cell functions. KIR2DS4 is one of the activating receptors in the KIR family and is particularly involved in identifying cells that may be infected, stressed, or tumorigenic. KIR receptors, including KIR2DS4, contribute to the immune system's adaptability through interactions with human leukocyte antigen (HLA) molecules, typically class I. However, unlike many KIR receptors that mediate inhibitory signals, KIR2DS4 is an activating receptor. It provides stimulatory signals that help NK cells become cytotoxic toward specific target cells. KIR genes, including KIR2DS4, are highly polymorphic, with substantial genetic variation between individuals, contributing to variations in immune response. KIR genes are clustered on chromosome 19, and their expression varies across different populations, impacting immune response diversity. This variation has implications for disease susceptibility, transplantation compatibility, and response to certain therapies.
Related Products
KIR2DS4 antibody
Receptor on natural killer(NK) cells for HLA-C alleles. Does not inhibit the activity of NK cells.
Ver Producto
Human Killer Cell Immunoglobulin Like Receptor 2DS4 (KIR2DS4) Protein
Human Killer Cell Immunoglobulin Like Receptor 2DS4 (KIR2DS4) is a recombinant Human protein expressed in E. coli.
Ver Producto
Killer Cell Immunoglobulin Like Receptor 2DS4 (KIR2DS4) Antibody
Polyclonal Antibody to Killer Cell Immunoglobulin Like Receptor 2DS4 (KIR2DS4).
Ver Producto