Kinase D-Interacting Substrate of 220 kDa (KIDINS220) Antibody

Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
Description
Kinase D-interacting substrate 220 Antibody is a Mouse Monoclonal antibody against Mouse.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Kinase D-Interacting Substrate of 220 kDa (KIDINS220) |
| Host | Mouse |
| Reactivity | Human, Mouse |
| Recommended Dilution | WB: 1/500 - 1/5000, IHC-P: 1/20, IF/ICC: 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Monoclonal |
| Conjugation | Unconjugated |
| Isotype | IgG1 |
| Clone ID | J805 |
| Purification | Purified by Protein A chromatography. |
| Size 1 | 100 µg |
| Form | Liquid |
| Tested Applications | WB, IHC, IF/ICC |
| Buffer | PBS, pH 7.4, containing 0.2% BSA, 40% glycerol and 0.05% sodium azide. |
| Availability | Shipped within 5-12 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q9ULH0 |
| Gene ID | 57498 |
| Background | Antibody anti-KIDINS220 |
| Status | RUO |
| Note | Concentration: 1 mg/ml - |
Descripción
Related Products

KIDINS220 antibody
Promotes a prolonged MAP-kinase signaling by neurotrophins through activation of a Rap1-dependent mechanism. Provides a docking site for the CRKL-C3G complex, resulting in Rap1-dependent sustained ERK activation. May play an important role in regulating postsynaptic signal transduction through the syntrophin-mediated localization of receptor tyrosine kinases such as EPHA4. In cooperation with SNTA1 can enhance EPHA4-induced JAK/STAT activation. Plays a role in nerve growth factor(NGF)-induced recruitment of RAPGEF2 to late endosomes and neurite outgrowth. May play a role in neurotrophin-and ephrin-mediated neuronal outgrowth and in axon guidance during neural development and in neuronal regeneration(By similarity). Modulates stress-induced apoptosis of melanoma cells via regulation of the MEK/ERK signaling pathway.
Ver Producto
Recombinant Human KIDINS220
Ver Producto
Kinase D-Interacting Substrate of 220 kDa (KIDINS220) Antibody
Kinase D-interacting substrate 220 Antibody is a Mouse Monoclonal antibody against Mouse.
Ver Producto