Adhesion G-Coupled Receptor L2 (ADGRL2) Antibody

Este producto es parte de ADGRL - Adhesion G protein-coupled receptor L
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273€ (100 µl)

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935106861
info@markelab.com
name
Adhesion G-Coupled Receptor L2 (ADGRL2) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx130893
tested applications
WB

Description

Adhesion G-Coupled Receptor L2 Antibody is a Rabbit Polyclonal against Adhesion G-Coupled Receptor L2.

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
Primary Antibodies
Immunogen Target
Target: Adhesion G-Coupled Receptor L2 (ADGRL2)
Immunogen: abx168635 -Recombinant LPHN2 (Val139-Pro398) expressed in E. coli.
Host
Rabbit
Reactivity
Rat
Assay Type
Concentration: 0.53 mg/ml
Recommended Dilution
WB: 0.01-2 µg/ml, IHC (Predicted): 5-20 µg/ml, IF/ICC (Predicted): 5-20 µg/ml. Optimal dilutions/concentrations should be determined by the end user.
Clonality
Polyclonal
Conjugation
Unconjugated
Purification
Purified by antigen-specific affinity chromatography, followed by Protein A affinity chromatography.
Size 1
100 µl
Size 2
200 µl
Size 3
1 ml
Form
Liquid
Tested Applications
WB
Buffer
0.01 M PBS, pH 7.4, containing 0.05% Proclin-300, 50% glycerol.
Availability
Shipped within 5-7 working days.
Storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Dry Ice
No
UniProt ID
O88923
Alias
ADGRL2,LPHN2,latrophilin 2,LPHH1,latrophilin homologue in humans 1,LEC1,lectomedin-1,CIRL2,calcium-independent receptor of alpha-latrotoxin 2,CL2,LEC1,LPHH1
Background
Antibody anti-ADGRL2
Status
RUO
Note
THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION.

Descripción

ADGRL2, or Latrophilin-2, is expressed across neuronal tissues and gastrointestinal organs, where it facilitates cellular adhesion and communication. Through its interaction with extracellular ligands and other adhesion molecules, ADGRL2 regulates synaptic formation, tissue organization, and intracellular signaling. This receptor is particularly significant in the gastrointestinal tract, where it contributes to tissue integrity and functional coordination. Its presence in neural tissues suggests a role in neurodevelopmental processes, synaptic organization, and intercellular signaling. ADGRL2’s involvement in cell adhesion mechanisms also suggests roles in maintaining homeostasis within epithelial and neuronal environments. Dysregulation or mutation of ADGRL2 has been associated with neurodevelopmental delays, gastrointestinal disorders, and altered cellular communication, making it a key target for research into both developmental and systemic diseases.

Related Products

abx168635

Rat Adhesion G-Coupled Receptor L2 (ADGRL2) Protein

Rat ADGRL2 Protein is a recombinant Rat protein expressed in E. coli.

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