Rat Adhesion G-Coupled Receptor L2 (ADGRL2) Protein

234€ (10 µg)
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935106861
info@markelab.com
name
Rat Adhesion G-Coupled Receptor L2 (ADGRL2) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx168635
tested applications
WB, SDS-PAGE
Description
Rat ADGRL2 Protein is a recombinant Rat protein expressed in E. coli.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | Adhesion G-Coupled Receptor L2 (ADGRL2) |
| Host | E. coli |
| Assay Type | Activity: Not tested Sequence Fragment: Val139-Pro398 Tag: N-terminal His tag |
| Origin | Rat |
| Conjugation | Unconjugated |
| Observed MW | Calculated MW: 33.7 kDa Observed MW (SDS-PAGE): 34 kDa |
| Expression | Recombinant |
| Purity | > 95% |
| Size 1 | 10 µg |
| Size 2 | 50 µg |
| Size 3 | 100 µg |
| Size 4 | 200 µg |
| Size 5 | 500 µg |
| Form | Lyophilized |
| Tested Applications | WB, SDS-PAGE |
| Buffer | Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300. |
| Availability | Shipped within 5-7 working days. |
| Storage | Store lyophilized form at 2-8°C for up to 1 month. For longer periods, store lyophilized or liquid at -80°C. Avoid repeated freeze–thaw cycles. |
| Dry Ice | No |
| UniProt ID | O88923 |
| Alias | ADGRL2,LPHN2,latrophilin 2,LPHH1,latrophilin homologue in humans 1,LEC1,lectomedin-1,CIRL2,calcium-independent receptor of alpha-latrotoxin 2,CL2,LEC1,LPHH1 |
| Background | Protein ADGRL2 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex. Concentration: Prior to lyophilization: 200 µg/ml |
Descripción
ADGRL2, or Latrophilin-2, is expressed across neuronal tissues and gastrointestinal organs, where it facilitates cellular adhesion and communication. Through its interaction with extracellular ligands and other adhesion molecules, ADGRL2 regulates synaptic formation, tissue organization, and intracellular signaling. This receptor is particularly significant in the gastrointestinal tract, where it contributes to tissue integrity and functional coordination. Its presence in neural tissues suggests a role in neurodevelopmental processes, synaptic organization, and intercellular signaling. ADGRL2’s involvement in cell adhesion mechanisms also suggests roles in maintaining homeostasis within epithelial and neuronal environments. Dysregulation or mutation of ADGRL2 has been associated with neurodevelopmental delays, gastrointestinal disorders, and altered cellular communication, making it a key target for research into both developmental and systemic diseases.
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