Mouse A Disintegrin And Metalloproteinase With Thrombospondin 7 (ADAMTS7) Protein

234€ (10 µg)
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935106861
info@markelab.com
name
Mouse A Disintegrin And Metalloproteinase With Thrombospondin 7 (ADAMTS7) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx065081
tested applications
WB, SDS-PAGE
Description
Mouse A Disintegrin And Metalloproteinase With Thrombospondin 7 (ADAMTS7) is a recombinant Mouse protein expressed in E. coli.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | A Disintegrin And Metalloproteinase With Thrombospondin 7 (ADAMTS7) |
| Host | E. coli |
| Assay Type | Activity: Not tested Sequence Fragment: Lys226-Pro437 Tag: N-terminal His tag |
| Origin | Mouse |
| Conjugation | Unconjugated |
| Observed MW | Calculated MW: 25.2 kDa Observed MW (SDS-PAGE): 27 kDa |
| Expression | Recombinant |
| Purity | > 90% |
| Size 1 | 10 µg |
| Size 2 | 50 µg |
| Size 3 | 100 µg |
| Size 4 | 200 µg |
| Size 5 | 500 µg |
| Form | Lyophilized |
| Tested Applications | WB, SDS-PAGE |
| Buffer | Prior to lyophilization: 20 mM Tris, 150 mM NaCl, pH 8.0, containing 1 mM EDTA, 1 mM DTT, 0.01% Sarcosyl, 5% Trehalose and Proclin-300. |
| Availability | Shipped within 5-7 working days. |
| Storage | Store lyophilized form at 2-8°C for up to 1 month. For longer periods, store lyophilized or liquid at -80°C. Avoid repeated freeze–thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q68SA9 |
| Alias | COMPase, Type 1 Motif 7,A Disintegrin And Metalloproteinase With Thrombospondin Motifs 7,ADAMTS-7,ADAM-TS 7 |
| Background | Protein ADAMTS7 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in 20 mM Tris, 150 mM NaCl, pH 8.0. If a higher concentration is required, the product can be reconstituted directly in 20 mM Tris, 150 mM NaCl, pH 8.0, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex. Concentration: Prior to lyophilization: 200 µg/ml |
Descripción
ADAMTS7 (A Disintegrin And Metalloproteinase with Thrombospondin Motifs 7) is another member of the ADAMTS family of proteases. Like other ADAMTS proteins, ADAMTS7 contains multiple domains, including a metalloproteinase domain, a disintegrin-like domain, and thrombospondin type-1 (TSP-1) motifs. ADAMTS7 is expressed in various tissues, including skeletal muscle, heart, brain, and cartilage. Its expression pattern suggests roles in tissue development, maintenance, and homeostasis. ADAMTS7 is implicated in various physiological processes, particularly in extracellular matrix (ECM) remodeling. It plays a role in the turnover and organization of ECM components, including proteoglycans and collagens. Additionally, ADAMTS7 has been linked to angiogenesis, inflammation, and wound healing.Dysregulation of ADAMTS7 has been associated with several diseases and conditions. In particular, ADAMTS7 has been implicated in osteoarthritis, where it may contribute to cartilage degradation and joint inflammation. Studies have also linked ADAMTS7 to atherosclerosis, where it may play a role in plaque formation and vascular remodeling.
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