Mouse Basal Cell Adhesion Molecule (BCAM) Protein (Active)
1118€ (100 µg)
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935106861
info@markelab.com
name
Mouse Basal Cell Adhesion Molecule (BCAM) Protein (Active)
category
Proteins and Peptides
provider
Abbexa
reference
abx692570
tested applications
SDS-PAGE
Description
Basal Cell Adhesion Molecule (BCAM) protein is a recombinant Mouse protein expressed in HEK293 cells.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | Basal Cell Adhesion Molecule (BCAM) |
| Host | HEK293 cells |
| Assay Type | Activity: Active Sequence Fragment: Met1-Ala541 Tag: C-terminal His tag |
| Origin | Mouse |
| Observed MW | 58.3 kDa |
| Expression | Recombinant |
| Purity | > 98% (SDS-PAGE) |
| Size 1 | 100 µg |
| Form | Lyophilized |
| Tested Applications | SDS-PAGE |
| Buffer | Prior to lyophilization: Sterile PBS, pH 7.4. |
| Availability | Shipped within 5-15 working days. |
| Storage | Storage: Store lyophilized between -20 °C and -80°C. Stability: Stable when stored reconstituted at 2-8°C for up to 1 week. Reconstituted aliquots are stable at -20°C for up to 3 months. Shelf Life: 12 months. |
| Dry Ice | No |
| UniProt ID | Q9R069 |
| Alias | Basal cell adhesion molecule,Lutheran blood group,AU,LU,B-CAM,CD239,MSK19,Auberger B antigen,B-CAM cell surface glycoprotein |
| Background | Protein BCAM |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. Endotoxin Level: < 1.0 EU per µg (LAL method). |
Descripción
Basal Cell Adhesion Molecule (BCAM), also known as Lu antigen or Lutheran antigen, is a type I membrane glycoprotein primarily expressed on the surface of erythrocytes (red blood cells) and other cell types, including endothelial cells and certain epithelial cells. BCAM belongs to the immunoglobulin superfamily of cell adhesion molecules (IgCAMs), which are involved in the adhesion between cells and the extracellular matrix. It is notably involved in the Lutheran blood group system, which plays an important role in blood transfusion medicine. BCAM is an important adhesion molecule that facilitates interactions between cells, as well as between cells and their extracellular matrix (ECM), thus contributing to tissue integrity and signaling processes. BCAM is critical in the endothelial cell junctions and erythrocyte adhesion to endothelial cells, thereby influencing processes like inflammation, vascular permeability, and cell migration. BCAM's expression on erythrocytes links it to important blood group antigens, which have clinical relevance in transfusion medicine, as well as in understanding the molecular mechanisms of various diseases, including autoimmune disorders, inflammatory diseases, and cancers.
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