Mouse Adhesion G Protein-Coupled Receptor V1 (ADGRV1) ELISA Kit

715€ (96 tests)
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935106861
info@markelab.com
name
Mouse Adhesion G Protein-Coupled Receptor V1 (ADGRV1) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx526078
tested applications
ELISA
Description
Mouse Adhesion G Protein-Coupled Receptor V1 (ADGRV1) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse Adhesion G Protein-Coupled Receptor V1 (ADGRV1) concentrations in serum, plasma, tissue homogenates, cell lysates and other biological fluids.
Documents del producto
Product specifications
| Category | ELISA Kits |
| Immunogen Target | Adhesion G Protein-Coupled Receptor V1 (ADGRV1) |
| Reactivity | Mouse |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Assay Type | Sandwich |
| Test Range | 78 pg/ml - 5000 pg/ml |
| Sensitivity | < 30 pg/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Form | Standard Form: Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Serum, plasma, tissue homogenates, cell lysates and other biological fluids. |
| Availability | Shipped within 5-15 working days. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | Q8VHN7 |
| Alias | ADGRV1,FEB4 GPR98,MASS1,USH2B,USH2C,VLGR1,VLGR1b |
| Background | Elisa Kits for: ADGRV1 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. The stability of the kit is determined by the rate of activity loss. The loss rate is less than 5% within the expiration date under appropriate storage conditions. To minimize performance fluctuations, operation procedures and lab conditions should be strictly controlled. It is also strongly suggested that the whole assay is performed by the same user throughout. |
Descripción
Adhesion G-protein coupled receptor V1 (ADGRV1), also known as GPR98, is a member of the adhesion GPCR family. ADGRV1 is a large transmembrane protein with an extracellular domain containing multiple adhesion motifs, a seven-transmembrane domain characteristic of G protein-coupled receptors (GPCRs), and an intracellular domain involved in signaling. ADGRV1 is primarily expressed in the inner ear and is essential for auditory function. It plays a crucial role in the development and maintenance of stereocilia, the specialized hair-like structures in the inner ear that detect sound vibrations and convert them into electrical signals. Mutations in the ADGRV1 gene are associated with various forms of hereditary hearing loss, including Usher syndrome type IIC and nonsyndromic deafness. These mutations disrupt the normal function of ADGRV1, leading to structural abnormalities in the stereocilia or impairment of signal transduction in the inner ear.
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