Mouse Ubiquitin Carboxyl Terminal Hydrolase L4 (UCHL4) Protein
234€ (10 µg)
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name
Mouse Ubiquitin Carboxyl Terminal Hydrolase L4 (UCHL4) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx168423
tested applications
WB, SDS-PAGE
Description
Mouse Ubiquitin Carboxyl Terminal Hydrolase L4 Protein is a recombinant Mouse protein expressed in E. coli.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | Ubiquitin Carboxyl Terminal Hydrolase L4 (UCHL4) |
| Host | E. coli |
| Assay Type | Activity: Not tested Sequence Fragment: Glu2-Ala233 Tag: N-terminal His tag |
| Origin | Mouse |
| Conjugation | Unconjugated |
| Observed MW | Calculated MW: 30.0 kDa |
| Expression | Recombinant |
| Purity | > 95% |
| Size 1 | 10 µg |
| Size 2 | 50 µg |
| Size 3 | 100 µg |
| Size 4 | 200 µg |
| Size 5 | 500 µg |
| Form | Lyophilized |
| Tested Applications | WB, SDS-PAGE |
| Buffer | Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300. |
| Availability | Shipped within 5-7 working days. |
| Storage | Store lyophilized form at 2-8°C for up to 1 month. For longer periods, store lyophilized or liquid at -80°C. Avoid repeated freeze–thaw cycles. |
| Dry Ice | No |
| UniProt ID | P58321 |
| Alias | Ubiquitin thioesterase L4 |
| Background | Protein UCHL4 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex. Concentration: Prior to lyophilization: 200 µg/ml |
Descripción
Ubiquitin C-Terminal Hydrolase L4 (UCHL4) is a member of the deubiquitinating enzyme family, which plays a critical role in the ubiquitin-proteasome system by removing ubiquitin moieties from ubiquitinated proteins. This process regulates protein degradation, turnover, and signaling pathways. UCHL4 is specifically involved in maintaining cellular ubiquitin homeostasis, thus influencing various cellular processes, including cell cycle progression, DNA repair, and stress responses. Dysregulation of UCHL4 activity has been implicated in pathological conditions such as cancer, where it may affect the stability of key oncogenes or tumor suppressors. Additionally, UCHL4 might have a role in neurodegenerative diseases through its function in protein quality control and aggregation prevention. Understanding its precise biological mechanisms is essential for exploring its potential as a therapeutic target in diseases associated with ubiquitin pathway dysregulation.
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