Muscleblind-Like Protein 1 (MBNL1) Antibody (Biotin)
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
Description
Muscleblind-like protein 1 Antibody (Biotin) is a Rabbit Polyclonal antibody against Muscleblind-like protein 1 conjugated to Biotin.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Muscleblind-Like Protein 1 (MBNL1) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Biotin |
| Isotype | IgG |
| Purity | > 95% |
| Purification | Purified by Protein G. |
| Size 1 | 20 µg |
| Size 2 | 50 µg |
| Size 3 | 100 µg |
| Size 4 | 200 µg |
| Size 5 | 1 mg |
| Form | Liquid |
| Tested Applications | ELISA |
| Buffer | 0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% Glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid exposure to light. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q9NR56 |
| Gene ID | 4154 |
| NCBI Accession | NP_001300986.1, NM_001314057.1 |
| OMIM | 160900 |
| Background | Antibody anti-MBNL1 |
| Status | RUO |
Descripción
Related Products
Muscleblind-Like Protein 1 (MBNL1) Antibody
MBNL1 Antibody is a Rabbit Polyclonal Antibody against MBNL1.
Ver Producto
Muscleblind-Like Protein 1 (MBNL1) Antibody
Mediates pre-mRNA alternative splicing regulation. Acts either as activator or repressor of splicing on specific pre-mRNA targets. Inhibits cardiac troponin-T (TNNT2) pre-mRNA exon inclusion but induces insulin receptor (IR) pre-mRNA exon inclusion in muscle. Antagonizes the alternative splicing activity pattern of CELF proteins. Regulates the TNNT2 exon 5 skipping through competition with U2AF2. Inhibits the formation of the spliceosome A complex on intron 4 of TNNT2 pre-mRNA. Binds to the stem-loop structure within the polypyrimidine tract of TNNT2 intron 4 during spliceosome assembly. Binds to the 5'-YGCU (U/G) Y-3'consensus sequence. Binds to the IR RNA. Binds to expanded CUG repeat RNA, which folds into a hairpin structure containing GC base pairs and bulged, unpaired U residues.
Ver Producto
Muscleblind-Like Protein 1 (MBNL1) Antibody (Biotin)
Muscleblind-like protein 1 Antibody (Biotin) is a Rabbit Polyclonal antibody against Muscleblind-like protein 1 conjugated to Biotin.
Ver Producto