Negative Elongation Factor Complex Member B (NELFB) Antibody

Name: Negative Elongation Factor Complex Member B (NELFB) Antibody
Brand: Abbexa
SKU: abx235657
Price: 377 EUR
Availability: OnlineOnly

377€ (100 µg)

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Negative Elongation Factor Complex Member B (NELFB) Antibody

Description

NELFB Antibody is a Rabbit Polyclonal against NELFB.

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Product specifications

Category	Primary Antibodies
Immunogen Target	Target: Negative Elongation Factor Complex Member B (NELFB) Immunogen: cofactor of BRCA1
Host	Rabbit
Reactivity	Human, Mouse, Rat
Assay Type	Concentration: 2 mg/ml
Recommended Dilution	WB: 1/500 - 1/2000, IF/ICC: 1/10 - 1/100, IP: 1/500 - 1/1000. Optimal dilutions/concentrations should be determined by the end user.
Clonality	Polyclonal
Conjugation	Unconjugated
Isotype	IgG
Observed MW	Observed MW: 66 kDa
Purity	≥ 95% (SDS-PAGE)
Purification	Purified by immunogen affinity chromatography.
Size 1	100 µg
Form	Liquid
Tested Applications	ELISA, WB, IF/ICC, IP
Buffer	PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol.
Availability	Shipped within 5-12 working days.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Dry Ice	No
UniProt ID	Q8WX92
Gene ID	25920
OMIM	611180
Background	Antibody anti-NELFB
Status	RUO
Note	THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION.

Descripción

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NELFB antibody

Essential component of the NELF complex, a complex that negatively regulates the elongation of transcription by RNA polymerase II. The NELF complex, which acts via an association with the DSIF complex and causes transcriptional pausing, is counteracted by the P-TEFb kinase complex. May be able to induce chromatin unfolding.

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