Neural Precursor Cell Expressed, Developmentally Down-Regulated 4, E3 Ubiquitin (NEDD4) Antibody
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
Description
NEDD4 Antibody is a Rabbit Polyclonal antibody against NEDD4. NEDD4-1(Neural precursor cell expressed developmentally down-regulated protein 4) is also named as NEDD4 and KIAA0093. It plays an essential role for the activation of the genetic program involved in the terminal maturation stage of invariant natural killer T-cell development(PMID:21949387). And it is differentially expressed in mammary epithelial cells and plays a role in luminal lineage determination(PMID:20351249). NEDD4-1 is a key regulator of FGFR1 endocytosis and signalling during neuronal differentiation and embryonic development(PMID:21765395). This antibody can recognize NEDD4-1 and NEDD4-2.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Neural Precursor Cell Expressed, Developmentally Down-Regulated 4, E3 Ubiquitin (NEDD4) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | IHC-P: 1/50 - 1/200. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified by affinity chromatography. |
| Size 1 | 60 µl |
| Size 2 | 120 µl |
| Size 3 | 200 µl |
| Form | Liquid |
| Tested Applications | IHC |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P46934 |
| Gene ID | 4734 |
| NCBI Accession | NP_940682.2 |
| Background | Antibody anti-NEDD4 |
| Status | RUO |
| Note | Concentration: 1 mg/ml - |
Descripción
Related Products
NEDD4 antibody
This gene is the founding member of the NEDD4 family of HECT ubiquitin ligases that function in the ubiquitin proteasome system of protein degradation. The encoded protein contains an N-terminal calcium and phospholipid binding C2 domain followed by multiple tryptophan-rich WW domains and, a C-terminal HECT ubiquitin ligase catalytic domain. It plays critical role in the regulation of a number of membrane receptors, endocytic machinery components and the tumor suppressor PTEN.
Ver Producto
Recombinant Human NEDD4
Ver Producto
Neural Precursor Cell Expressed, Developmentally Down-Regulated 4, E3 Ubiquitin (NEDD4) Antibody
NEDD4 Antibody is a Rabbit Polyclonal antibody against NEDD4. NEDD4-1(Neural precursor cell expressed developmentally down-regulated protein 4) is also named as NEDD4 and KIAA0093. It plays an essential role for the activation of the genetic program involved in the terminal maturation stage of invariant natural killer T-cell development(PMID:21949387). And it is differentially expressed in mammary epithelial cells and plays a role in luminal lineage determination(PMID:20351249). NEDD4-1 is a key regulator of FGFR1 endocytosis and signalling during neuronal differentiation and embryonic development(PMID:21765395). This antibody can recognize NEDD4-1 and NEDD4-2.
Ver Producto