NACHT, LRR And PYD Domains-Containing Protein 12 (NLRP12) Antibody
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Description
NLRP12 Antibody is a Rabbit Polyclonal Antibody against NLRP12.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Target: NACHT, LRR And PYD Domains-Containing Protein 12 (NLRP12) Immunogen: Recombinant fusion protein corresponding to human NLRP12 |
| Host | Rabbit |
| Reactivity | Rat |
| Assay Type | Concentration: 1 mg/ml |
| Recommended Dilution | WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | Calculated MW: 31 kDa/101 kDa/107 kDa/113 kDa/114 kDa/120 kDa Observed MW: 120 kDa |
| Purification | Purified by affinity chromatography. |
| Size 1 | 60 µl |
| Size 2 | 120 µl |
| Size 3 | 200 µl |
| Form | Liquid |
| Tested Applications | WB |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P59046 |
| Gene ID | 91662 |
| NCBI Accession | NP_653288.1 |
| Background | Antibody anti-NLRP12 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Descripción
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This gene encodes a member of the CATERPILLER family of cytoplasmic proteins. The encoded protein, which contains an N-terminal pyrin domain, a NACHT domain, a NACHT-associated domain, and a C-terminus leucine-rich repeat region, functions as an attenuating factor of inflammation by suppressing inflammatory responses in activated monocytes. Alternatively spliced transcript variants encoding distinct isoforms have been described but the full-length nature of some of these has not been determined.
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