PAS Domain-Containing Serine/threonine-Protein Kinase (PASK) Antibody
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Description
PASK Antibody is a Rabbit Polyclonal against PASK.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | PAS Domain-Containing Serine/threonine-Protein Kinase (PASK) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1/500 - 1/2000, IHC: 1/20 - 1/200, IF/ICC: 1/20 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purity | ≥ 95% (SDS-PAGE) |
| Purification | Purified by immunogen affinity chromatography. |
| Size 1 | 100 µg |
| Form | Liquid |
| Tested Applications | ELISA, WB, IHC, IF/ICC |
| Buffer | PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol. |
| Availability | Shipped within 5-12 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q96RG2 |
| Gene ID | 23178 |
| OMIM | 607505 |
| Background | Antibody anti-PASK |
| Status | RUO |
| Note | Concentration: 2 mg/ml - Validity: 12 months. |
Descripción
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PASK antibody
Serine/threonine-protein kinase involved in energy homeostasis and protein translation. Phosphorylates EEF1A1, GYS1, PDX1 and RPS6. Probably plays a role under changing environmental conditions(oxygen, glucose, nutrition), rather than under standard conditions. Acts as a sensor involved in energy homeostasis: regulates glycogen synthase synthesis by mediating phosphorylation of GYS1, leading to GYS1 inactivation. May be involved in glucose-stimulated insulin production in pancreas and regulation of glucagon secretion by glucose in alpha cells; however such data require additional evidences. May play a role in regulation of protein translation by phosphorylating EEF1A1, leading to increase translation efficiency. May also participate to respiratory regulation.
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PAS Domain-Containing Serine/threonine-Protein Kinase (PASK) Antibody
PASK Antibody is a Rabbit Polyclonal Antibody against PASK.
Ver Producto
PAS Domain-Containing Serine/threonine-Protein Kinase (PASK) Antibody
PASK Antibody is a Rabbit Polyclonal against PASK.
Ver Producto