Phd Finger Protein 11 (PHF11) Antibody
637€ (100 µl)
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
Name
Phd Finger Protein 11 (PHF11) Antibody
Category
Primary Antibodies
Provider
Abbexa
Reference
abx114418
Tested Applications
ELISA, WB, IHC
Description
Phd Finger Protein 11 Antibody is a Rabbit Polyclonal antibody against Phd Finger Protein 11.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: Phd Finger Protein 11 (PHF11) Immunogen: Human PHF11. |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Antigen Affinity Chromatography. |
| Size 1 | 100 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB, IHC |
| Buffer | PBS, pH 7.3, containing 0.1% Sodium Azide and 50% Glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q9UIL8 |
| Gene ID | 51131 |
| NCBI Accession | NP_001035533.1, NM_001040443.2 |
| OMIM | 147050 |
| Alias | PHF11,BCAP,NY-REN-34,IGER,BRCA1 C-Terminus-Associated Protein,Renal Carcinoma Antigen NY-REN-34,NYREN34,IGHER,IGEL,APY |
| Background | Antibody anti-PHF11 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Background
PHF11 is a PHD domain-containing protein involved in transcriptional regulation and immune responses. It interacts with transcription factors and chromatin modifiers to regulate the expression of genes associated with inflammation, immune cell activation, and DNA repair. PHF11 plays a key role in enhancing transcriptional activity at specific genomic loci, particularly in B cells and T cells, where it regulates immune responses, including cytokine production and class-switch recombination. It is highly expressed in lymphoid tissues, supporting its role in adaptive immunity and lymphocyte function. Dysregulation of PHF11 is associated with autoimmune diseases, inflammatory disorders, and cancer, where altered transcriptional regulation disrupts immune balance and cell proliferation. Knockout studies demonstrate impaired immune responses, reduced antibody production, and defective lymphocyte activation, highlighting its importance in transcriptional regulation, immune system maintenance, and adaptive immunity.
Productos relacionados
PHD Finger Protein 11 (PHF11) Antibody
PHF11 Antibody is a Rabbit Polyclonal Antibody against PHF11.…
Ver producto Phd Finger Protein 11 (PHF11) Antibody
Phd Finger Protein 11 Antibody is a Rabbit Polyclonal antibody against Phd Finger Protein 11.…
Ver producto