Proline-Serine-Threonine Phosphatase-Interacting Protein 1 (PSTPIP1) Antibody
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
Description
PSTPIP1 Antibody is a Rabbit Polyclonal Antibody against PSTPIP1.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Target: Proline-Serine-Threonine Phosphatase-Interacting Protein 1 (PSTPIP1) Immunogen: Recombinant protein corresponding to PSTPIP1. The exact sequence is proprietary. |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Assay Type | Concentration: > 0.2 mg/ml |
| Recommended Dilution | ELISA: 1 µg/ml, WB: 1/500 - 1/2000, IHC-P: 1/50 - 1/200. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | Calculated MW: 48 kDa Observed MW: 48 kDa |
| Purification | Purified by affinity chromatography. |
| Size 1 | 20 µl |
| Size 2 | 100 µl |
| Size 3 | 2 × 100 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB, IHC |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | O43586 |
| Gene ID | 9051 |
| NCBI Accession | NP_003969.2 |
| Background | Antibody anti-PSTPIP1 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Descripción
Related Products
PSTPIP1 antibody
This gene encodes a cytoskeletal protein that is highly expressed in hemopoietic tissues. This protein functions via its interaction with several different proteins involved in cytoskeletal organization and inflammatory processes. It binds to the cytoplasmic tail of CD2, an effector of T cell activation and adhesion, downregulating CD2-triggered adhesion. It binds PEST-type protein tyrosine phosphatases (PTP) and directs them to c-Abl kinase to mediate c-Abl dephosphorylation, thereby, regulating c-Abl activity. It also interacts with pyrin, which is found in association with the cytoskeleton in myeloid/monocytic cells and modulates immunoregulatory functions. Mutations in this gene are associated with PAPA (pyogenic sterile arthritis, pyoderma gangrenosum, and acne) syndrome. It is hypothesized that the disease-causing mutations compromise physiologic signaling necessary for the maintenance of a proper inflammatory response.
Ver Producto
Recombinant Human PSTPIP1
Ver Producto
Proline-Serine-Threonine Phosphatase-Interacting Protein 1 (PSTPIP1) Antibody
PSTPIP1 Antibody is a Rabbit Polyclonal Antibody against PSTPIP1.
Ver Producto