Protein Phosphatase 1 Regulatory Subunit 8 (PPP1R8) Antibody

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195€ (20 µl)

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935106861
info@markelab.com
name
Protein Phosphatase 1 Regulatory Subunit 8 (PPP1R8) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx005140
tested applications
ELISA, WB, IHC, IF/ICC

Description

PPP1R8 Antibody is a Rabbit Polyclonal antibody against PPP1R8. This gene, through alternative splicing, encodes three different isoforms. Two of the protein isoforms encoded by this gene are specific inhibitors of type 1 serine/threonine protein phosphatases and can bind but not cleave RNA. The third protein isoform lacks the phosphatase inhibitory function but is a single-strand endoribonuclease comparable to RNase E of E. coli. This isoform requires magnesium for its function and cleaves specific sites in A+U-rich regions of RNA.

Documents del producto

Instrucciones
Data sheet
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Product specifications

Category
Primary Antibodies
Immunogen Target
Protein Phosphatase 1 Regulatory Subunit 8 (PPP1R8)
Host
Rabbit
Reactivity
Human, Mouse, Rat
Recommended Dilution
ELISA: 1 µg/ml, WB: 1/500 - 1/2000, IHC-P: 1/50 - 1/200, IF/ICC: 1/50 - 1/100. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Clonality
Polyclonal
Conjugation
Unconjugated
Isotype
IgG
Purification
Purified by affinity chromatography.
Size 1
20 µl
Size 2
100 µl
Size 3
2 × 100 µl
Form
Liquid
Tested Applications
ELISA, WB, IHC, IF/ICC
Buffer
PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.
Availability
Shipped within 5-10 working days.
Storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Dry Ice
No
UniProt ID
Q12972
Gene ID
5511
NCBI Accession
NP_612568.1
Background
Antibody anti-PPP1R8
Status
RUO
Note
Concentration: > 0.2 mg/ml -

Descripción

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PPP1R8 Antibody is a Rabbit Polyclonal antibody against PPP1R8. This gene, through alternative splicing, encodes three different isoforms. Two of the protein isoforms encoded by this gene are specific inhibitors of type 1 serine/threonine protein phosphatases and can bind but not cleave RNA. The third protein isoform lacks the phosphatase inhibitory function but is a single-strand endoribonuclease comparable to RNase E of E. coli. This isoform requires magnesium for its function and cleaves specific sites in A+U-rich regions of RNA.

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