Rat Ywhaz (14-3-3 protein zeta/delta) ELISA Kit
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Name
Rat Ywhaz (14-3-3 protein zeta/delta) ELISA Kit
Category
ELISA Kits
Provider
FineTest
Reference
ER0532
Tested Applications
ELISA
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | ELISA Kits |
| Reactivity | Rat |
| Detection Method | Colorimetric |
| Assay Data | 4 hours |
| Assay Type | Sandwich ELISA, Double Antibody |
| Test Range | 31.25-2000pg/ml |
| Sensitivity | 18.75pg/ml |
| Size 1 | 96T |
| Tested Applications | ELISA |
| Sample Type | Serum, Plasma, Cell Culture Supernatant, cell or tissue lysate, Other liquid samples |
| Availability | Shipped within 10-14 working days. |
| Storage | 2-8 °C for 12 months |
| UniProt ID | P63102 |
| Alias | YWHAZ, 14-3-3-zeta, HEL-S-3, HEL4, KCIP-1, YWHAD, HEL-S-93, tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta, POPCHAS |
| Background | Elisa kits for YWHAZ |
| Status | RUO |
Background
YWHAZ, a member of the 14-3-3 protein family, is a highly conserved adaptor protein that regulates signal transduction by binding to phosphorylated serine/threonine residues on target proteins. It functions as a molecular scaffold, facilitating protein-protein interactions involved in diverse cellular processes, including cell cycle progression, apoptosis, and signal transduction. YWHAZ plays a role in regulating pathways such as PI3K/Akt, MAPK, and TGF-β, influencing cell survival, proliferation, and migration. It is abundantly expressed in the brain and immune tissues, where it is critical for neuronal development, synaptic plasticity, and stress responses. Dysregulation of YWHAZ is implicated in neurological disorders, cancer progression, and metabolic diseases due to its role in stabilizing oncogenic and signaling proteins. Knockout studies reveal defects in brain development, increased apoptosis, and impaired cell signaling, underscoring its essential role as a key regulator of cellular homeostasis and signaling pathways.
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