Sialic Acid Binding Ig Like Lectin 12 (SIGLEC12) Antibody
312€ (60 µl)
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935106861
info@markelab.com
name
Sialic Acid Binding Ig Like Lectin 12 (SIGLEC12) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx006214
tested applications
WB
Description
SIGLEC12 Antibody is a Rabbit Polyclonal Antibody against SIGLEC12.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Target: Sialic Acid Binding Ig Like Lectin 12 (SIGLEC12) Immunogen: Recombinant fusion protein corresponding to human SIGLEC12 |
| Host | Rabbit |
| Reactivity | Mouse |
| Assay Type | Concentration: 1 mg/ml |
| Recommended Dilution | WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | Calculated MW: 51 kDa/64 kDa Observed MW: 80 kDa |
| Purification | Purified by affinity chromatography. |
| Size 1 | 60 µl |
| Size 2 | 120 µl |
| Size 3 | 200 µl |
| Form | Liquid |
| Tested Applications | WB |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q96PQ1 |
| Gene ID | 89858 |
| NCBI Accession | NP_443729.1 |
| Alias | S2V,SLG,SIGLECL1,Siglec-XII,Sialic acid-binding Ig-like lectin-like 1,Siglec-12 |
| Background | Antibody anti-SIGLEC12 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Descripción
SIGLEC12 is an atypical Siglec that has lost its sialic acid-binding capacity in humans due to evolutionary mutations. It is expressed in some epithelial tissues and immune cells. Although its function remains poorly understood, SIGLEC12 has been linked to inflammation and cancer, where its altered expression might promote tumor progression.
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