Steroid Hormone Receptor ERR1 (ESRRA) Antibody
195€ (20 µl)
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name
Steroid Hormone Receptor ERR1 (ESRRA) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx006697
tested applications
ELISA, WB, IF/ICC
Description
ESRRA Antibody is a Rabbit Polyclonal Antibody against ESRRA.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Target: Steroid Hormone Receptor ERR1 (ESRRA) Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-76 of human ESRRA. |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Assay Type | Concentration: > 0.2 mg/ml |
| Recommended Dilution | ELISA: 1 µg/ml, WB: 1/500 - 1/2000, IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | Calculated MW: 46 kDa Observed MW: 53 kDa |
| Purification | Purified by affinity chromatography. |
| Size 1 | 20 µl |
| Size 2 | 100 µl |
| Size 3 | 2 × 100 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB, IF/ICC |
| Buffer | PBS, pH 7.3, containing 0.09% sodium azide, 50% glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P11474 |
| Gene ID | 2101 |
| NCBI Accession | NP_004442.3 |
| Alias | ERR1,ERRa,ESRL1,NR3B1,ERRalpha,Steroid hormone receptor ERR1,Estrogen receptor-like 1,Nuclear receptor subfamily 3 group B member 1 |
| Background | Antibody anti-ESRRA |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Descripción
Estrogen related receptor alpha (ESRRA) is a nuclear receptor that is involved in regulating energy metabolism, mitochondrial function, and cellular differentiation ESRRA, also known as ERRα, is activated in response to metabolic signals and plays a central role in regulating the expression of genes involved in oxidative metabolism, fatty acid oxidation, and glucose homeostasis It is highly expressed in tissues with high metabolic activity, such as the heart, liver, and muscle, where it helps maintain cellular energy balance by modulating mitochondrial biogenesis and function ESRRA is also important for maintaining normal brain function, bone homeostasis, and cardiovascular health Dysregulation of ESRRA has been linked to metabolic disorders such as obesity, type 2 diabetes, and cardiovascular diseases, as well as certain types of cancer where altered mitochondrial function and energy metabolism contribute to tumor growth ESRRA represents a potential target for therapies aimed at enhancing metabolic health and preventing diseases related to mitochondrial dysfunction
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