TBC1 Domain Family Member 5 (TBC1D5) Antibody

Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
Description
TBC1D5 Antibody is a Rabbit Polyclonal against TBC1D5.
Documents del producto
Product specifications
Category | Primary Antibodies |
Immunogen Target | TBC1 Domain Family Member 5 (TBC1D5) |
Host | Rabbit |
Reactivity | Human, Mouse, Rat |
Recommended Dilution | WB: 1/500 - 1/2400, IHC: 1/20 - 1/200, IP: 1/200 - 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
Clonality | Polyclonal |
Conjugation | Unconjugated |
Isotype | IgG |
Purity | ≥ 95% (SDS-PAGE) |
Purification | Purified by immunogen affinity chromatography. |
Size 1 | 100 µg |
Form | Liquid |
Tested Applications | ELISA, WB, IHC, IP |
Buffer | PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol. |
Availability | Shipped within 5-12 working days. |
Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
Dry Ice | No |
UniProt ID | Q92609 |
Gene ID | 9779 |
OMIM | 615740 |
Background | Antibody anti-TBC1D5 |
Status | RUO |
Note | Concentration: 2 mg/ml - Validity: 12 months. |
Descripción
Related Products

TBC1D5 antibody
May act as a GTPase-activating protein(GAP) for Rab family protein(s). May act as a GAP for RAB7A. Can displace RAB7A and retromer CSC subcomplex from the endosomal membrane to the cytosol; at least retromer displacement seems to require its catalytic activity(PubMed:19531583, PubMed:20923837). Required for retrograde transport of cargo proteins from endosomes to the trans-Golgi network(TGN); the function seems to require its catalytic activity. Involved in regulation of autophagy(PubMed:22354992). May act as a molecular switch between endosomal and autophagosomal transport and is involved in reprogramming vesicle trafficking upon autophagy induction. Involved in the trafficking of ATG9A upon activation of autophagy. May regulate the recruitment of ATG9A-AP2-containing vesicles to autophagic membranes(PubMed:24603492).
Ver Producto
Recombinant Human TBC1D5
Ver Producto
TBC1 Domain Family Member 5 (TBC1D5) Antibody
TBC1D5 Antibody is a Rabbit Polyclonal against TBC1D5.
Ver Producto