Toll-Like Receptor 10 (TLR10) Antibody
357.5€ (100 µg)
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935106861
info@markelab.com
name
Toll-Like Receptor 10 (TLR10) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx145419
tested applications
ELISA, WB, IHC
Description
TLR10 Antibody is a Rabbit Polyclonal against TLR10.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Target: Toll-Like Receptor 10 (TLR10) Immunogen: Recombinant fragment corresponding to 605-764 AA of human TLR10. |
| Host | Rabbit |
| Reactivity | Human |
| Assay Type | Concentration: Lyophilized form: Not applicable. After reconstitution: 1 mg/ml. |
| Recommended Dilution | ELISA: 1/20000 - 1/80000, WB: 1/500 - 1/2000, IHC: 1/100 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | Observed MW: 95 kDa |
| Purification | Purified by antigen affinity column chromatography. |
| Size 1 | 100 µg |
| Size 2 | 1 mg |
| Form | Lyophilized |
| Tested Applications | ELISA, WB, IHC |
| Buffer | Prior to lyophilization: 1% BSA and 0.02% NaN3. |
| Availability | Shipped within 7-15 working days. |
| Storage | Store at -20 °C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| NCBI Accession | BC109112 |
| Alias | Toll-like receptor 10,CD290 |
| Background | Antibody anti-TLR10 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Descripción
Toll-like receptor 10 (TLR10) is the only human TLR with an entirely unknown ligand and functional role, marking it as a unique and enigmatic member of the Toll-like receptor (TLR) family. This family plays essential roles in innate immunity by recognizing pathogen-associated molecular patterns (PAMPs) and initiating immune responses. Despite its unclear ligand specificity, TLR10 is hypothesized to play regulatory roles, particularly in modulating immune responses. In humans, TLR10 is primarily expressed in lymphoid tissues such as the spleen, lymph nodes, tonsils, and the immune cells within these tissues, including B cells, dendritic cells (DCs), and monocytes. TLR10 is expressed alongside TLRs that typically recognize nucleic acids or microbial components, which suggests that it may function in coordination with other TLRs to fine-tune immune responses, potentially acting as a regulatory or inhibitory receptor.
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