Transcription Elongation Factor B Subunit 2 (TCEB2) Antibody

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273€ (100 µg)

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935106861
info@markelab.com
name
Transcription Elongation Factor B Subunit 2 (TCEB2) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx018171
tested applications
ELISA, WB

Description

TCEB2 Antibody is a Mouse Monoclonal antibody against TCEB2.

Documents del producto

Instrucciones
Data sheet
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Product specifications

Category
Primary Antibodies
Immunogen Target
Transcription Elongation Factor B Subunit 2 (TCEB2)
Host
Mouse
Reactivity
Human
Recommended Dilution
Optimal dilutions/concentrations should be determined by the end user.
Clonality
Monoclonal
Conjugation
Unconjugated
Isotype
IgG1
Purification
Purified from ascites by Protein A chromatography.
Size 1
100 µg
Form
Liquid
Tested Applications
ELISA, WB
Buffer
Citrate-Tris-HCl, pH 7.0, with 0.02% Proclin-300.
Availability
Shipped within 5-10 working days.
Storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Dry Ice
No
NCBI Accession
NM_007108
Background
Antibody anti-TCEB2
Status
RUO
Note
Concentration: 1 mg/ml -

Descripción

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TCEB2 Antibody is a Rabbit Polyclonal antibody against TCEB2. This gene encodes the protein elongin B, which is a subunit of the transcription factor B (SIII) complex. The SIII complex is composed of elongins A/A2, B and C. It activates elongation by RNA polymerase II by suppressing transient pausing of the polymerase at many sites within transcription units. Elongin A functions as the transcriptionally active component of the SIII complex, whereas elongins B and C are regulatory subunits. Elongin A2 is specifically expressed in the testis, and capable of forming a stable complex with elongins B and C. The von Hippel-Lindau tumor suppressor protein binds to elongins B and C, and thereby inhibits transcription elongation. Two alternatively spliced transcript variants encoding different isoforms have been described for this gene. Pseudogenes have been identified on chromosomes 11 and 13.

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