Trifunctional Enzyme Subunit Beta, Mitochondrial (HADHB) Antibody

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195€ (20 µl)

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935106861
info@markelab.com
name
Trifunctional Enzyme Subunit Beta, Mitochondrial (HADHB) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx004370
tested applications
ELISA, WB, IF/ICC

Description

HADHB Antibody is a Rabbit Polyclonal antibody against HADHB. This gene encodes the beta subunit of the mitochondrial trifunctional protein, which catalyzes the last three steps of mitochondrial beta-oxidation of long chain fatty acids. The mitochondrial membrane-bound heterocomplex is composed of four alpha and four beta subunits, with the beta subunit catalyzing the 3-ketoacyl-CoA thiolase activity. The encoded protein can also bind RNA and decreases the stability of some mRNAs. The genes of the alpha and beta subunits of the mitochondrial trifunctional protein are located adjacent to each other in the human genome in a head-to-head orientation. Mutations in this gene result in trifunctional protein deficiency. Alternatively spliced transcript variants encoding different isoforms have been described.

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Product specifications

Category
Primary Antibodies
Immunogen Target
Trifunctional Enzyme Subunit Beta, Mitochondrial (HADHB)
Host
Rabbit
Reactivity
Human, Mouse, Rat
Recommended Dilution
ELISA: 1 µg/ml, WB: 1/500 - 1/1000, IF/ICC: 1/10 - 1/100. Optimal dilutions/concentrations should be determined by the end user.
Clonality
Polyclonal
Conjugation
Unconjugated
Isotype
IgG
Purification
Purified by affinity chromatography.
Size 1
20 µl
Size 2
100 µl
Size 3
2 × 100 µl
Form
Liquid
Tested Applications
ELISA, WB, IF/ICC
Buffer
PBS, pH 7.3, containing 0.05% Proclin-300, 50% glycerol.
Availability
Shipped within 5-10 working days.
Storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Dry Ice
No
UniProt ID
P55084
Gene ID
3032
NCBI Accession
NP_000174.1
Alias
Acetyl-CoA acyltransferase,Beta-ketothiolase
Background
Antibody anti-HADHB
Status
RUO
Note
Concentration: > 0.2 mg/ml -

Descripción

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