VWF, VWFpp Antibody
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Description
VWF, VWFpp Antibody is a Rabbit Polyclonal against VWF, VWFpp.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | VWF, VWFpp |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1/200 - 1/2000, IHC: 1/100 - 1/400. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purity | ≥ 95% (SDS-PAGE) |
| Purification | Purified by immunogen affinity chromatography. |
| Size 1 | 100 µg |
| Form | Liquid |
| Tested Applications | ELISA, WB, IHC |
| Buffer | PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol. |
| Availability | Shipped within 5-12 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P04275 |
| Background | Antibody anti-VWF, VWFpp |
| Status | RUO |
| Note | Concentration: 2 mg/ml - Validity: 12 months. |
Descripción
Related Products
VWF, VWFpp antibody
Von Willebrand factor(vWF) is a large multimeric glycoprotein that is crucial to the hemostasis process. It supports platelet adhesion and carries factor VIII(FVIII). Deficiency of vWF results in von Willebrand disease(vWD), a common inherited bleeding disorder. The pre-pro-vWF is comprised of 2,813 amino acids(aa) which encompass a 22-aa signal peptide, a 741-aa large propeptide(vWF propeptide, vWFpp, also called von Willebrand antigen II) and 2,050 aa making up the mature vWF. The von Willebrand antigen 2 is required for multimerization of vWF and for its targeting to storage granules. This antibody raised against the N-terminal region of pre-pro-vWF recognizes von Willebrand antigen 2(75-83 kDa) and pro-vWF(309-320 kDa).
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