Zinc Finger FYVE Domain-Containing Protein 19 (ZFYVE19) Antibody
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Description
ZFYVE19 Antibody is a Rabbit Polyclonal antibody against ZFYVE19.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Zinc Finger FYVE Domain-Containing Protein 19 (ZFYVE19) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | WB: 1/1000, IHC-P: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Size 1 | 80 µl |
| Size 2 | 400 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB, IHC |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q96K21 |
| Background | Antibody anti-ZFYVE19 |
| Status | RUO |
Descripción
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Key regulator of abscission step in cytokinesis: part of the cytokinesis checkpoint, a process required to delay abscission to prevent both premature resolution of intercellular chromosome bridges and accumulation of DNA damage. Together with CHMP4C, required to retain abscission-competent VPS4(VPS4A and/or VPS4B) at the midbody ring until abscission checkpoint signaling is terminated at late cytokinesis. Deactivation of AURKB results in dephosphorylation of CHMP4C followed by its dissociation from ZFYVE19/ANCHR and VPS4 and subsequent abscission.
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Zinc Finger FYVE Domain-Containing Protein 19 (ZFYVE19) Antibody
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ZFYVE19 Antibody is a Rabbit Polyclonal antibody against ZFYVE19.
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